Sunday, February 4, 2007

Questions from January 22, 2007

1. If the distance between base pairs in .34 nm and there are 6 billion base pairs in each human cell, then the total distance of all base pairs strectched end-to-end would be 2.04 billion nm or 2.04 m.
(0.34nm * 6,000,000,000 bp = 2,040,000,000nm / 1,000,000,000(nm/m) = 2.04m)

Since there are 100 trillion cells in the body, that means that if all the DNA in every was stretched end-to-end the total length would be 204 trillion meters long or 204 billion kilometers.
(2.04m * 100,000,000,000,000 cells = 204,000,000,000,000m / 1000(m/km) = 204,000,000,000km)

2. (picture)

3. Since Chargaff's rule states that %A = %T and %G = %C the B19 virus does not follow Chargaff's rule. This suggests that either the virus reproduces in a different way (highly unlikely) or that it needs to take on bases from another source to survive and duplicate.

4. The major error in the video is quickly evident. If you watch carefully when the double helix divides at the beginning of the video nucleotides begin attaching to the separated end of the DNA molecule but because DNA helices are anti-parallel nucleotides on both backbones cannot attach going the same direction. Essentially DNA can only replicate in the 5' to 3' direction but in this video it is replicating in both directions.

No comments: